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Study finds that Fatal blood clots Can cause in women due to birth control pills and painkiller



Women who take common painkillers in addition to taking birth control pills run the risk of developing potentially fatal blood clots, according to a new warning from researchers. When combined with hormonal contraception, the use of non-steroidal anti-inflammatory drugs (NSAIDs) like Nurofen raises the risk of blood clots, also known as venous thromboembolism, according to the study.

When compared to women who used progestin-only pills, implants, or intrauterine devices (IUDs) alongside nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, diclofenac, and naproxen, the risk was found to be higher for women who used combined oral contraceptives that contained progestins of the third or fourth generation.

The specialists underscore that the general gamble of fostering an extreme blood clump stays low, even among ladies utilizing high-risk hormonal contraception. In any case, given the far and wide utilization of both hormonal contraception and NSAIDs, they propose that ladies ought to be educated about the expected dangers.

In spite of the fact that NSAIDs have been recently connected to blood clusters, little is had some significant awareness of what their utilization means for the gamble of blood clumps in any case sound ladies who are additionally utilizing hormonal contraception. The Danish team used national medical records to track two million women between the ages of 15 and 49 who lived in Denmark between 1996 and 2017 who were first diagnosed with blood clots. These ladies had no set of experiences of blood clumps, malignant growth, hysterectomy, or fruitfulness treatment.

Based on their association with venous thromboembolism, various hormonal contraceptives were categorized as high, medium, or low risk in previous studies. The new concentrate likewise represented a scope of possibly persuasive factors, for example, age, instruction level, pregnancy history, earlier medical procedures, hypertension, and diabetes.

NSAIDs were utilized by the greater part 1,000,000 ladies while they were on hormonal contraception. Ibuprofen was the most generally utilized NSAID, comprising 60% of use, trailed by diclofenac at 20% and naproxen at six percent. 8,710 venous thromboembolic events occurred during an average 10-year monitoring period, and 228 women (2.6 percent) died within 30 days of being diagnosed.

“Using high quality, linkable, national registries, this nationwide study adds new knowledge on the risk of a potentially fatal event during concomitant use of two drug classes often prescribed to otherwise healthy women,” says study author Dr. Amani Meaidi from the University of Copenhagen, in a media release. “Women needing both hormonal contraception and regular use of NSAIDs should be advised accordingly.”

In addition, the findings raise “important concerns” regarding using diclofenac and high-risk hormonal contraception simultaneously. When determining whether or not over-the-counter diclofenac is safe, the team suggests that health authorities take these findings into account. Moreover, the two ladies on the pill and their PCPs ought to think about options in contrast to NSAIDs for help with discomfort.

“If treatment with NSAIDs is needed, agents other than diclofenac seem preferable, along with lower risk hormonal contraceptives such as progestin only tablets, implants, or intrauterine devices,” says Professor Morten Schmidt from Aarhus University Hospital.


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